Pantazopoulos played for Panellinios and Panathinaikos. With Panathinaikos, as a player/coach, he won 3 Greek championships (1946, 1947, 1950) and 2 local Athens-Piraeus championships (1947, 1950). As a coach, he won the Greek championship in 1951 for Panathinaikos.
Pantazopoulos was capped 9 times by the National Basketball Team of Greece scoring 18 points and was a member of the Eurobasket 1949 team that won bronze in Egypt. He coached the National Basketball Team at various times between 1956 and 1969.