As Gibraltar was a British overseas territory, Pacifico was recognised as a British subject.
In 1850, he was a key figure in the international crisis known as the Pacifico incident. Living and working in Athens for a period of time, first as the Portuguese consul and later as a private businessman, in 1847 his home was attacked and vandalised by a mob that included the sons of a government minister, whilst the police looked on and took no action. He appealed to the Greek government for compensation for loss of possessions and documents relating to a substantial claim against the Portuguese government for monies owed, but when it was not forthcoming he appealed in 1848 to the British.
He died in London.