Blanco started his career with Colón de Santa Fe in 2002. He then played for Club Libertad in Paraguay in 2005 before returning to Argentina to play for Olimpo de Bahía Blanca. In 2007 he rejoined Colón.
On 10 August 2007 Blanco joined AEK. His desire to display his football talent in Europe and the opportunity to play on the same squad as Brazilian legend Rivaldo where stated as his main reasons for making the move to Greece.
His career in Greece
- Primera B Nacional: Apertura Top Scorer: 2006
- Primera B Nacional: Clausura Top Scorer: 2007
- Alpha Ethniki: Top Scorer: 2008
- Alpha Ethniki: Top Scorer: 2009 (jointly with Luciano Galletti of Olympiakos)
When Blanco scores a goal he slips on a Zorro mask he keeps hidden in his stocking or does a dance resembling the Batusi dance.