Lefkaritis was born on 28 November 1946 in Lemesos, Cyprus. He led a successful career as a shipping and petroleum executive while involving himself in the administrative aspect of football at first locally with Apollon Limassol.
After serving five years on the board of Apollon, Lefkaritis was admitted to the board of the Cyprus Football Association (KOP) in 1985. He served as the organisation's president from 1991 until 2001.
Lefkaritis is also an Executive Committee member of UEFA since 1996, currently serving as its vice-president and treasurer.
He is also a member of the Executive Committee of FIFA.
Lefkaritis is married with three daughters.