- January 15: France supplies the Kemalist army with weapons and ammunition in the Greco-Turkish War (1919-1922).
- February 7: The first issue of Athens daily "To Vima" (The Podium) is published. Among the newspapers' founders is Dimitrios Lambrakis.
- March 13: Kemal Ataturk turns down an offer of a ceasefire during the Greco-Turkish War (1919-1922) insisting that the Greek Army first vacate Asia Minor and Eastern Thrace.
- March 31: During the Greco-Turkish War (1919-1922), the Sultan's army join forces with the Kemalists.
- April 20: The Italians sign a separate treaty with the Kemalists, agreeing to withdraw from Asia Minor. Their zone of occupation had been directly south of the Greek zone.
- May 16: Nikolaos Stratos forms a government. He will fail to win a vote of confidence and will quit 6 days later.
- May 22: Petros Protopapadakis forms a government.
- June 23: Alexandros Papanastasiou is sentenced to three years imprisonment for publishing his "Democratic Manifesto". His defence lawyer had been George Papandreou.
- July 18: The Greek government declares Asia Minor independent, after truce signing negotations with Turkey fail.
- july 31: With a signed document, Panathinaikos president Giorgos Hatzopoulos, who designed the 3-leaf clover and general secretary, Mihalis Papazoglou, who selected it, announce the new name of Panathinaikos, from PPAO to PAO
- August 26: The Battle of Afyon Karahisar commences.
- August 30: The Battle of Afyon Karahisar ends in defeat for the Greek army.
- September 9: Turkish troops enter Smyrna.
- September 10: Bishop Chrysostom of Smyrna is slain by a lynch mob.
- September 13: Smyrna is set ablaze by the Turkish army. For the next three days the city will burn out of control and an estimated 100,000 Greeks and Armenians will be killed.
- September 24: Greek soldiers under Stylianos Gonatas and Nikolaos Plastiras, as well as sailors under Dimitrios Fokas, rebel against and overthrow the Athens government.
- September 27: King Constantine I abdicates the throne.
- September 30: Metropolitan Gregorios of Kydonies, along with 22 priests of Ayvali are lynched by Turkish irregulars. The clergymen had stayed on to assist in the evacuation of the city by its Greek population.
- October 11: The Armistice of Mudanya is signed between Britain, France, Italy on the one hand and Turkey on the other.
- October 14: Greece acceeds to the Armistice of Mudanya.
- October 20: The peace conference which eventually produces the Treaty of Lausanne, commences.
- October 22: The Greek army evacuates Eastern Thrace followed by thousands of Greek and Armenian refugees.
- October 22: A huge demonstration takes place in central Athens as thousands demand the execution of those responsible for the Asia Minor disaster.
- October 25: An order is issued for a special military court to convene and pass judgement against those deemed responsible for the Asia Minor disaster.
- November 13: Seven high-ranking members of the Laiko Party and General Georgios Hadjianestis go before a military court on charges of high treason for their role in the Asia Minor disaster.
- November 28: Five members of the Laiko Party - Dimitrios Gounaris, Nikolaos Stratos, Petros Protopapadakis, Nikolaos Theotokis, Georgios Baltatzis - as well as General Georgios Hadjianestis are executed at 10:30 am, in Goudi, Athens, for their role in the Asia Minor disaster. The court's decision had been announced three hours earlier.
- December 3: War rallies are held in many Cypriot cities with the union between Greece and Cyprus being the main demand.
- February 22: Apostolos Santas, member of the Greek Resistance who lowered the swastika from the Acropolis, Athens.